It is Keika-chan.
Epileptic seizures + diarrhea, who had increased antiepileptic drugs, appetite diminished desire to lower appetite appeared, it came to pass through the fourth day.
Keika-chan also got some medicine in epileptic seizures! ! February 27, 2019
Keika-chan was dripping with anorexia .... March 3, 2019
Is Chu-ru the source of pancreatitis? · Keika-chan intravenous second day March 4, 2019
Keika-chan who came a little lively Subcutaneous drip on day 3 March 5, 2019
Not all meet, but about 80% can be eaten.
There is not a momentary moment yet ,,,
Today I went to the hospital to drip, I decided to see a little at home.
I injected 100 ml infusion subcutaneously on my back.
Keika chan, today's weight is 3.02 kg, which is a very small amount. 😢
(Originally 3.1 kg)
As a human being 60 kg people are like 2 L subcutaneous injections, I am worried that it will be okay, but it seems okay for cats to be fine as they pull skin.
When I told that my urine had increased, I was told that I do not have to worry because I have an injection.
It is absorbed also by subcutaneous injection.
(It does not make sense if it does not)
By the way, when you take rice which you recently bought and ask, "How about high nutrition food around here?
"When you do not eat together with Chu-ru"
She said.
It seems that it is not something to give too often after all. . .
Today is also 4212 yen.
For the time being, Coneve decided to see "1/6 tablets 2 times a day twice" for a while.
It would be nice to be able to eat as it is.
Because cats get older at 4 times faster than people, they say that sickness will get worse at 4 times faster, but it is not quadrupling better. . .
*
It was the reason that this time Keika - chan stopped eating meals because I had a seizure a week ago.
Keika-chan also got some medicine in epileptic seizures! ! February 27, 2019
① There was a change in physical condition that caused a seizure (diarrhea?), Causing a seizure and I could not eat meal.
② I got a seizure and changed my medicine and I could not eat meal.
These two are conceivable,
Once on Thursday I almost eat meal as usual,
I think that it is ②.
The veterinarian says, "Drug has increased and it is too effective."
So,
How long does medicine remain in the body?
Regarding the antiepileptic drugs examined in the last blood concentration,
I investigated anti-epileptic drug (zonisamide / diazepam / valproic acid) and blood concentration February 26, 2019
Next time I studied about half life.
*Note*
I gathered this information personally and summarized.
It is not responsible for diagnostic treatment and accuracy.
For individual diseases please consult with your hospital etc on your own.
Half-life is the time until the concentration of the drug in the body is halved.
If it is a drinking medicine, go from the mouth to the stomach, intestine, it is absorbed into the blood from the intestine, and it turns into the body by blood. Therefore, it exerts its effect in organs (brains with epilepsy) which are the object of drug effect. However, since it is basically a foreign matter, it will not remain in the body forever, it will be metabolized by the liver and kidneys and discharged outside the body.
So, in order to keep on the effect, I take medicine every day.
First of all,
Zonisamide (ZNS)
It is an anti epilepsy medicine returned by Conseb, Keika-chan.
Half-life is 600 mg, 63 hours.
63 hours? What?
Two and a half days? What? What?
Long time! ! !
It takes time to get out if this amount is large, which is tough. .
Certainly increased medicine, appetite and cheer disappeared from Friday the 2nd day, medicine has decreased since Sunday night, it is recovering on Wednesday, so it is roughly matched.
Diazepam (DZP)
It is a die-up suppository at the time of this attack.
Here, 10 mg rectal administration, 35 hours
35 hours. .
Is it one day and nine hours? .
It is quite effective time, is not it?
Sodium valproate (VPA)
In addition, I studied, antiepileptic drug valproic acid for humans.
This is an ordinary medicine, there is a sluggish slow release agent gradually eluting from the tablet.
For ordinary medicine, 600 mg, 9.5 hours
Sustained release formulation at 600 mg for 13 hours
was.
Well, zonisamide, it will remain in the body well.
You have to be careful not to drink too much.
Also be careful not to misunderstand administration.
original Japanese version → 抗てんかん薬（ゾニサミド・ジアゼパム・バルプロ酸）の半減期・桂花ちゃん点滴一旦終了 2019年3月6日
